Risk of Combining Coffee and Carbohydrates

Surely you’ve heard before that it is best to try getting the majority of your daily carbohydrates early. Many of us have a hardy, carb-heavy meal at breakfast. With this let me make one point…avoid that morning cup of coffee! Unless of course it is De-Caf!

Now if you are anything like me you are asking…why?…why? How can I go without my morning wake up, right?

Ok, it has been recommended that eating your greatest amount of carbs at breakfast is because glucose tolerance and blood insulin sensitivity are greater in the early hours of the day. Mornings are the time of day the body is better equipped to handle carbohydrates and as the day goes on this ability diminishes. Coffee (caffeinated) seems to have an acute negative effect on the body’s glucose tolerance and insulin sensitivity processing of carbs in the morning and logically weakens later in the day.

There have been quite a few studies on this subject, here are a couple:

“Caffeine & Insulin Resistance
14 Nov 2010… Caffeine was found to reduce insulin sensitivity in response to a high-carbohydrate meal, in a 2010 “British Journal of Nutrition” study. Participants were given 5 mg caffeine per kg body weight, along with a high-sugar cereal and three hours later an oral glucose tolerance test of 75 g glucose. The group that had consumed caffeine showed higher blood glucose and higher insulin levels than control groups that consumed a decaffeinated beverage or water. The researchers concluded that caffeine was helpful in managing insulin and blood glucose levels in the presence of high glycemic index foods. Read more: http://www.livestrong.com/article/306817-caffeine-insulin-resistance/#ixzz1W9iNTCe8 “

“Caffeine Insulin Resistance Affect?
Journal of Caffeine Research
March 2011…”Caffeine and Coffee
Can Impair Glucose Regulation…New research shows coffee & caffeine drinks can double blood glucose levels & increase risk of Type II Diabetes…A brand new study, published in the Journal of Caffeine Research shows the health dangers of drinking coffee and caffeine. http://www.all-about-beating-diabetes.com/caffeine-insulin-resistance-affect.html “

This indicates that if you are ingesting a high or even low glycemic index meal such as high sugar cereals or processed white flour products with caffeinated coffee (or energy drink) you can damage considerably your body’s ability to manage blood glucose and insulin sensitivity in comparison to having a decaffeinated coffee or drink instead.

It is suggested that consuming caffeinated drinks in general is better when not consuming large or generous portions of carbohydrates. So you can change to decaf in the mornings with your favorite breakfast. Also, in many of the articles read it was suggested that when working out a carbohydrate beverage for recovery should not be consumed with a caffeine boost. Cutting back on the sugars and highly processed foods is also better for you in the long run.

Burn extra fat?

Are you one of those individuals, who are in search of some effective weight loss product? Have you tried all kinds of weight loss program and still didn’t manage to get the desired result? Don’t worry. Here’s great news for you. A new product called Herbalife Total Control is launched. It is an effective weight loss solution and can bring in great results for all. This product is very simple and simply reduces the fat in no time.

It works wonder because it is made in such a way that it performs directly with body’s cellular composition to check the cravings for food, enhances metabolic activities. You can use Herbalife Total Control without sacrificing the food you love most. By taking this herbal supplement you can maintain the perfect weight. Moreover, you will also experience an increase in your energy levels.

This weight loss supplement contains the unique mix of components, which helps in weight loss. The ingredients like green tea and yerba mate increases metabolic activities. The other ingredients like damiana, quercetin and DL-phenylalanine support the natural fat burning process. The ginger extract in Herbalife Total Control regulates the working of digestive system. LilyHealth.com

Above all, the ingredients in the this product mend the immune system, check blood pressure and also flushes out the harmful toxins from your body. As a result, you will always feel refreshed and renewed. Herbalife Total Control is absolutely a great way to get back your health back on track. So, visit its official website and order a pack as soon as possible

Important Facts About Very Low Calorie Diets

Lots of people have different opinions about very low calorie diets. There are people that think it is the best way to lose weight and people that say they are not healthy. If you want to start a diet like this then you should contact your doctor and get your own information about it. The following facts about very low calorie diets can be a good starting point for your research.

Sticking to a very low calorie diet is often something people struggle with, which is a problem. Consuming less than 800 calories a day is very difficult to maintain for a long period of time. Once coming off the diet people tend to gain weight again, when they lost it on the diet. To help you in the long term, it is a good idea to come up with a strategy for eating healthier and changing your lifestyle. That way, you can lose some weight quickly with a very low calorie diet, and then, rather than going back to your old habits, you can eat a modified diet that’s still healthy while exercising regularly too.

To ensure that you stay within the limit of your calories, most very low calorie diets will have some sort of formula that’s prepared, however there are some diets that severely restrict your calories which are natural. A raw foods diet is one option, where you simply consume foods that aren’t cooked or processed. A raw foods diet that’s strict will not be high in calories due to you keeping away from all processed and high calorie foods.

Normally a raw foods diet will be made up of fruits, nuts, sprouts and vegetables, however it’s possible to make your own versions of raw foods like bread by simply using a dehydrator. Lots of people find it rather difficult to stay on track with this kind of diet because eating most everyday foods is forbidden, however this is considered to be healthy. If you aren’t too keen on making your diet 100% raw then you may wish to add some more raw foods into your very low calorie diet.

Burn extra fat?

Figure Competition Supplements

While competing in a figure competition takes desire, hard work, and focused dedication, many times natural supplements can play an important role for maintaining your health, boosting your metabolism, lowering body fat, and even building lean muscle tissue. In this short article I am going to reveal to you some of the top figure competition supplements to help you reach your figure contest goal of competing and winning.

First and foremost, you should, without a doubt, include a natural, full-spectrum multi-vitamin in your figure contest diet program. Figure contest prep requires a structured and somewhat strict diet program, which is often low in calories. By supplementing your figure prep diet with a multi-vitamin of quality, you can be sure that you are receiving all the nutrients you need to lose body fat and build lean muscle mass safely.

Figure competition supplements are not limited to just multi-vitamins. Through hard training and strict dieting practices, you can tap into your glutamine stores, draining them. To prevent precious muscle loss, it is ideal to supplement your figure competition diet with the popular all-natural sports nutrition supplement, glutamine.

Simply by supplementing 5-20 grams of glutamine to your figure prep program you can spare a good amount of lean muscle mass and burn body fat instead.

Some of the best figure competition supplements are some of the most popular, such as protein drinks.

Protein drinks and shakes can give you a good injection of needed protein to maintain lean muscle mass and burn body fat. Simply by adding a scoop or two of whey protein to your figure contest diet each day, you can bump-up your protein intake by a massive 50 grams.

A lot of figure competition supplements also can boost training intensity and performance such as creatine. Creatine is basically a cell-volumninzer, meaning it pushes water into your muscle cells, swelling them up a little allowing you to train harder and longer. Don’t get this confused with water retention, which is water under the skin. By taking a mere 5 grams of creatine every day, you will boost your training intensity, muscle gains, and fat loss.

Burn extra fat?

Foods for a Healthy Long Life

Aging as the name suggests includes all the physical and physiological changes that occur in the body as the body ages. This includes not only skin but all other bodily functions as well. Anti-aging refers to the slowing and to some extent reversal process. Healthy lifestyle that includes moderate exercise and a healthy diet can definitely delay the aging.

Age related changes can be reversed by consuming foods which are rich in anti-oxidants.

There are certain foods which can help preventing cell degeneration. General guidelines would be to have whole grains, plenty of fruits and vegetables and less saturated fat. There are some foods which are exceptionally help full in the anti-ageing.

1. Green vegetables – Green vegetables help keep the body weight low and also help fight toxins. Cruciferous vegetables like cabbage, cauliflower, broccoli and sprouts help the body in itís fight against toxins and cancer. If possible try to eat them raw or very lightly cooked so that the enzymes remain intact.

2. All berries, especially Gooseberries, are very rich in vitamin C and therefore highly useful to the body. Vitamin C helps in proper blood circulation and provides minerals and salts to all the body parts. Needless to say this helps the body to fight against aging and keep fit.

3. Avocados – Avacado is one of the most alkaline food available. It is also rich in vitamin E which is essential for glowing skin and shining hair. This fruit, which is usually eaten as a vegetable, is a good source of healthy monosaturated fats that may help to reduce level of a bad type o This fruit, which is usually eaten as a vegetable, is a good source of healthy monosaturated fats that help to reduce bad cholesterol in the body. Avocado is a good source of vitamin E and can help to maintain healthy skin and prevent skin aging.

4. Berries – all blue and black berries contain anti-oxidants protect the body against damage caused by free radicals.

5. Ginger – This spicy root boosts the digestive and circulatory system. It also helps to ease rheumatic pains.

6. Garlic – It prevents cell degeneration and helps keep the blood thin. It helps prevent heart disease. It is highly beneficial when eaten raw.

7. Nuts – Nuts are good source of minerals and improve the functioning of digestive and immune system. Nuts also help to control cholesterol levels.

8. Water melon – Both the flesh and seeds are nutritious. Melons contain lot of vitamins and provide the body with essential fluids.

9. Yogurt – is rich is important minerals like potassium, calcium, protein and B vitamins. Apart from these, what makes yogurt one of the most powerful foods is the presence of live bacteria in it. This bacteria helps absorption of nutrients in the intestines and stabilizes the immune system.

10. Green Tea – Green tea acts an anti-viral agent. It contains fluoride that prevents cavities as well as strengthens tooth enamel.

11. Water – Drink at least 8 glasses of water every day to keep healthy. It helps us get rid of toxins and waste materials.

Burn extra fat?

Life Extension Metabolic Pathway Map Reveals New Phytonutrient Candidates

The three most common and deadly diseases of aging are atherogenic cardiovascular disease, the cancers and diabetes II. The metabolic pathway conferring life extension has just recently been outlined. The three disease metabolic pathways run in direct opposition to the life extension pathway. We have generated a metabolic flow chart (map) that shows both systems as a dynamic singularity. We make sense of these diseases and life extension in the text, in terms of the metabolic map. From a compendium of phytonutrients, we discovered a small handful of them that satisfied a very stringent set of criteria for fighting these diseases and accomplishing genuine life extension. The three most successful candidates form a remarkable fit in terms of our metabolic map, while the five runners up are very close fits. Used singly, or in combination, all eight have found efficacy in treating many dozens of age related diseases beyond the three main killers we describe, herein. Introduction

The most common and deadly diseases of aging are the 1) atherosclerotically induced cardiovascular disease group, 2) middle age onset type II diabetes and 3) the multitudinous array of cancers. Obesity might be considered a fourth disease, but since its morbidity usually manifests its outcome as a consequence of one or more of the first three diseases, it will only be treated in an ancillary fashion, as a condition. All these diseases share, at their causative core, a metabolic pattern of imbalances that are remarkably similar. Viewed superficially, this does not appear to be the case, because they operate in different physiological compartments and at different levels of cellular organization. For instance, in cancer, the metabolic pattern operates at the intracellular level, and in fact, can begin in a single cell. Extracellular physiological manifestations of cancer become evidenced at the multicellular level, much later, as mesenchymal and metastatic 3D tumor invasion and dispersal. Diabetes requires the mobilization of trillions of cells working in concert at the tissue and organ level of integration. Atherosclerotic cardiovascular disease also involves the participation of gaggles of cells operating at the level of the vascular tree. The common denominator includes mal adaptations to carbohydrate metabolism that become fixed and self exacerbating, ultimately leading to each disease having characteristic forms of outcomes.

Recent developments give us three great proofs that the aforementioned statements are true. First, the same metabolic pathways and/or their downstream destructive outputs are evidenced in all three disease situations. Second, and more importantly, pharmaceutical or phytonutrient metabolic pathway differential rectifiers prevent, delay onset, delay progression, and in some cases, actually reverse all three disease states with a single therapeutic regimen. Lastly, pushing the metabolic system in the reverse direction of its multiple disease manifestations actually extends life beyond its normal time span limit. This is multi-serendipity enough to induce a lustful search for an Occam’s razor.

The Phytonutrient/Nutriceutical Candidates

The health food stores and giant pharmacy chains are awash with a bewildering array of hundreds, if not thousands of natural (and otherwise) dietary food supplements and herbal extracts from the four corners of the world. Just walking down the aisles should institute some form of clinical depression. Where to begin? How does one separate the questionable legitimacies of; folk remedies, old wives’ tales, heap big mojo shamanism, venerable ancient medical wisdom, mythology, cultural favorites, modern marketing snake oil hucksterism etc. from actual fact and good medicine? As an alternative to taxing our already enfeebled brains, we hit on the best idea we’ve had in years. Instead of embarking on an interminable grand search, we let the world’s best and brightest topic specific professional brains do our thinking for us, and we went in with a strategic plan.

We embraced a copy Disease Prevention and Treatment, published by The LifeExtension Foundation (LEF). Therein lies the combined efforts of ‘thousands of research studies and the clinical experience of physicians around the world’ (to put it in LEF’s own words) devoted to the over riding purpose of life extension. After reviewing what LEF had to say, we used scientific publications and the internet to update and modernize our understanding. Having our CG/CM and CR/LE map in hand, and our three principal diseases to both direct our search and institute the strategic plan, we plunged in.

The plan had a few simple but inviolate and all inclusive rules. Each candidate must have utility against multiple cancers and against diabetes and against atherogenesis; all three. It must both, statistically prevent or delay onset of all three diseases by significantly reducing the probability of age related population incidence and must slow the progression of all three disease states, once disease is instituted. Where the principle target and/or mechanisms of action are known, it must regulate its target, and in turn, their downstream pathway targets in the direction consistent with the CG/CM and CR/LE map. Where principle target or mechanism of action is not yet known, downstream effects must match the regulatory directions of our metabolic map. Although not an absolute requirement, each chemical should have an extremely high LD-50, in the multiple dozens to hundreds of times its functional dynamic range and a history of extreme safety, which all our winners do. The probability of satisfying all of these and requirements is minute and is a powerful set for a true candidate.

Limiting our search from the world at large to the LEF compendium, instantly whittled the search from thousands of possibilities to a few hundred. Applying the all inclusive rule set to these few hundred, fairly quickly drove the number down to a few dozen and then, much more slowly and agonizingly, chipped its way down to a handful. Incidentally, route of administration was not a consideration as some of these molecules have poor oral bioavailability in a pure form, but much higher bioavailability in a soluble injectable form, or in a conjugated oral form. Winning candidates might be more accurately defined as nutriceuticals rather than as phytonutrients or dietary supplements due to their mechanism of action. We have already provided a general description of the differential therapeutic merits of our gold medal and silver medal winners, and we will diversify those merits and differentials, later.

Before we begin, we must say a word or two, about antioxidants. For one thing, antioxidants are good for us, plain and simple. Thus, it is not surprising that antioxidants have been all the rage for the last two decades, and for a host of good reasons. They protect us from the major diseases of aging, reduce ROS formation, give us more vitality and with a long list of well worn etceteras, allow the population survival curve to leptokurticly shift toward the maximum life expectancy. However, they simply do not institute LE, albeit being ‘the best game in town’. Driving this point home is that organisms on a CR or CR mimetic protocol manifest LE without any antioxidant supplementation whatsoever! Check and mate. End of game.

For this and other reasons the ROS damaging hypothesis is now seen more from the avoidance of the life shortening side, as opposed to the life lengthening side of the equation. The antioxidant hypothesis has been found to be limited and in need of modification. We must remember here, that critical elements of the LE pathway were only discovered during the last one to two years, so a theory modification was not even realistically possible prior the very recent present. For instance, the LE pathway institutes mitochondrial regenesis and reduces ROS production, in the first place, obviating the need to mop up ROS ‘after the fact’ with antioxidants. Prior to the elucidation of the LE pathway, any LE system activator would have been, and in fact was called an antioxidant, simply because of mitochondrial regenesis; and mitochondrial regenesis was not hypothesized at the time. We believe ourselves to be the first folks to attempt to formulate a primitive global CG/CM and CR/LE map that includes the notions of cancer metabotype, mitochondrial neogenesis/regenesis, CR/LE pathway, CG/CM pathway, CR/LE pathway mimetic and functional antioxidant classification as simple antioxidant, funnel antioxidant and metabolic pathway antioxidant, even though all of these things are well described in the literature, but disjointed, because this age of specialization obscures any ‘big picture’ review approach, such as ours.

The health food supplement world is awash in phytonutrient antioxidants, and our metabolic map has helped us to loosely classify them into three broad categories with considerable overlap. Simple antioxidants are, to put it simply, basically just antioxidants. Vitamin C is a simple antioxidant. In fact, if it doesn’t have a partner to defuse it, it becomes a pro-oxidant in its ROS activated state. Funnel antioxidants are antioxidants that both accept ROS from other antioxidants and pass their ROS activated electron(s) to a metabolic system to defuse them and to extract useful energy. For instance, the vitamin C, vitamin E, NAD sequence, sets vitamin E as a funnel antioxidant. Better yet, a little system like coenzyme Q (CoQ) and alpha lipoic acid funnel ROS energy from ROS and many other antioxidants, with CoQ being a requisite functional element in the metabolic pathway itself, for passing ROS electrons to the OX/PHOS system of mitochondria for energy capture as ATP production. In addition, alpha lipoic acid restores vitamin E and vitamin C to full antioxidant status by reducing their oxidized state; a possible recycling alternative to massive simple antioxidant dosing. Best of all, are giant macromolecular machine system antioxidants such as the mitochondrial OX/PHOS efficiency system of mitochondrial regenesis, as turned on by activated CR/LE. This third category is the big antioxidant player in our new understanding of the CR/LE phenomenon. Now, we are in a position to consider the functions of our winning candidates. Lastly, we are not going to list all of the impacts of our gold and silver medal winners, or this narrative would read like a phone book. We will bundle wherever possible and stick to main effects, hopefully, without short changing the reader.

The three big gold medal winners are curcumin, silibinin andresveratrol. Cumin root can be partially purified to turmeric, taken as is, or further purified to its most active ingredient, curcumin. Milk thistle extract, called silymarin, can also be taken as is, or can be purified to its most active component, silibinin. Resveratrol is most often alcohol extracted from waste grape skins or Japanese knot weed roots, and provided as an impure mixture of about 80/20 to 60/40 ratio of phytosterols to resveratrol and consumed as is. It is also available in its most active form, trans-resveratrol. All three are cheap, readily available, have a long historical tradition, own a virtually immaculate safety record, are unpatentable and are causing pharmaceutical companies to rip their hair out by the roots, in exasperation. On the pharmaceutical upside, is that the companies are assiduously pursuing better, more biochemically focused, patentable and more expensive pharmaceutical alternative mechanism of action variants. But, until then, we are stuck with the natural stuff. Because their overall impacts and principal active sites are so similar, as described below, we bundle all three together. Of course, as downstream mitochondrial regenesis activators, all have been historically listed as powerful antioxidants, but now we know better.

As succinctly as possible, all three gold medalists down regulate AKT, COX II, inflammatory IL cytokines, NF-kB, HIF, VEGF, angiogenesis, fasting insulin, insulin resistance, LDL, blood glucose, HbA1c, ROS, all incidence and rate phases of cancer cell initiation, progression, proliferation and invasion, as well as all the phases in the liver steatosis/cirrhosis/MS/diabetes sequence and the atherogenic cardiovascular and related disease processes and groups, to name a few. In addition, they all up regulate apoptosis, autophagy, insulin sensitivity, AMPK, P53, insulin dependant receptors, heart and skeletal muscle oxygen consumption, ATP output, mitochondrial numbers, force of contraction, hepatogenesis, neurogenesis, mitochondrial regenesis, antioxidant response and multiple type cancer cell differentiation and disease victim survival time, also, to name a few. These data imply that that they must be operating upstream of TOR, close to a main input branch of TOR, perhaps on the CR side not far from AMPK, due to strong AMPK and p53 system up regulation in the absence of evidence supporting a very strong AKT, P13K, or RAS down regulation. A little over a year ago, Affymetrix gene chip shotgun analysis showed that resveratrol activated exactly the same near 1,000 gene set activated by CR downstream of AMPK in all tissues tested. While writing this paper, we learned, after our map had predicted it, that curcumin activated the same gene set. We suspect a similar outcome for silibinin, as it has been recently found to directly, or close to directly, up regulate P53 and its down stream cancer suppressor protein P21. These interactions with AMPK may be complex, because P53 is up regulated in all three cases, which seemingly, should not occur with simple or direct AMPK activation. The rather soft down activation of the CG/CM pathway shows itself to be due to cross regulatory pathway inhibition by such factors as activated P53, partial TOR block and halting of the mitochondrial RTG response, rather than due to direct pathway inhibitors.

Oral bioavailability of curcumin, silibinin and resveratrol is poor, in all cases. Oral bioavailability of curcumin increases 2,000% when mixed with piperine from black pepper. Silibinin is obtainable as bioavailable conjugates of several kinds. Resveratrol is available as lozenges to support buccal absorption, or is provided in pure form, in mega-doses. Resveratrol conjugation would not work orally, because it is converted to kidney eliminable glucoronides and sulfonates in the intestine and liver on the first blood pass through these organs, which occurs prior to the first pass to the somatic tissues.

The remaining candidates failed to make our rigorous gold medal cut for one reason or another, but they are not slouches by any means, and that is why we give them the high status of the word ‘silver medal’. The silver medalists are all excellent supplements and form powerful synergies with each other and the other three big gold medal winners. Unfortunately, all three gold medalists only exert their main effect on the CR/LE pathway, depending entirely on regulatory CR/LE elements to inhibit CG/CM. Some of our silver medal winners are direct CG/CM down regulators, while others are CR/LE reinforcers, and one is even a ‘shotgun’ multi-system synergizer.

The shotgun synergizer is a real powerhouse, a whole system appearing to have been evolved to operate it. It is the omega 3/6 essential oil mix available from flax seed oil, fish oil or krill oil, with flax being by far, the least expensive. The most important are the 18 carbon omega 6 linoleic acid, the 18 carbon omega 3 linolenic acid, the 20 carbon omega 3 eicosopentanoic acid (EPA) and the 20 carbon omega 3 docohexanoic acid (DHA). These fatty acids incorporate into cell membranes and give them durable integrity, reducing brittleness and thus, increasing all membrane dependant cell function efficiency. They are metabolized to become a number of cell system activators and inhibitors. For instance, the DHA and EPA pathway products reduce arachidonic acid, IL1, COX II and TNF induced inflammation. Other impacts include increasing apoptosis and immune surveillance, and reducing cancer cell proliferation, cachexic wasting and angiogenesis. They act as anti-metastatic, anti-HIF, anti-VEGF and are essential for mitochondrial cardiolipin production, which is critical in the function of the mitochondrial complexes III and IV in the respiratory chain. The American diet is seriously deficient in omega 3/6; some say suicidally deficient, containing less that 10% of the healthy minimum needed.

Another synergistic beauty is alpha lipoic acid. The Linus Pauling institute considers it to be one of the most powerful antioxidants known. Of all of the winners listed, it would be classified as a zoonutrient, but is only actually available as a synthetic, as natural source isolation is ridiculously expensive. Fortunately, its structure is so ‘dirt’ simple that its synthesis is also ‘dirt’ cheap. It can be regenerated from its oxidized form by glutathione. It is also a funnel anti-oxidant, regenerating vitamin C, vitamin E, the ubiquinone form of CoQ and all the while, destroying a wide array of ROS. It reduces NF-kB and foam cell production and renders regenic mitochondria more efficient. In fact, alpha lipoic acid preferentially locates to mitochondria, where it has the most ROS reduction impact. This strongly supports the CR/LE side of the equation.

Coenzyme Q (CoQ) runs along similar lines as alpha lipoic acid but its primary function is more specific. It is a powerful antioxidant in its own right, but preferentially locates to mitochondrial respiratory complex I, where it increases net mitochondrial ATP production. This activates glutathione production in the liver. Glutathione is the most powerful antioxidant produced by the body and is a key alpha lipoic acid regenerator. Glutathione has multiple impacts all over the LE system. CoQ has long been used in Japan to fight congestive heart failure and left ventricular hypertrophy by increasing cardiac ATP production and force of contraction. CoQ assists the CR/LE pathway to achieve its fully intended mitochondrial regenic efficiency.

The most active ingredient in green and white tea is epigallo catechin gallate (EGCG) while the most active component in soy extract is genestein. They both inhibit the CG/CM pathway somewhere downstream of the growth factors and upstream of AKT. There is some evidence that EGCG operates somewhere between growth factors and RAS. They both have broad spectrum tumor anti-proliferative activity, and where measured, down regulate the CG/CM to TOR upstream activators. Finally, we have CG/CM down regulators to complement our three gold medal CR/LE activators! With further research, maybe EGCG and genestein might someday be elevated to big winner status.

Vitamin K, or more significantly vitamin K2, might someday be included as a player on the CG/CM side of the equation, as it is a tyrosine phosphatase inhibitor of vital elements in the cell growth cascade. Inositol hexaphosphate also has CG/CM possibilities. A new kid on the block and creating quite a stir is moringa oleifera extract. According to the promotional claims, it has all the right biochemical pathway bells and whistles, and like most of the winner and honorable mention extracts, in their crude form, is loaded with polyphenols. Maybe there is a magical one in the mix, or it’s just the whole mix. We look forward to a scientific paper battery to substantiate or refute the claims. There also might be a few more winners among the supplements already in common use that simply have not yet been tested within the framework of the CG/CM or CR/LE system.

Conclusion

We all know that there is no perfection in this real world, and we are far from projecting perfection herein. Animal studies show that CR and CR mimetics induce LE, even when started during the pre-adult growth phase. They do not inhibit normal mitosis or cell differentiation, but the resultant animals have slightly smaller cells and body size. Until we are sure, it would seem to be prudent not to apply CR mimetics or CG inhibitors when pregnant, still growing, taking intentional ROS generating cancer chemotherapy or suffering from GH deficient dwarfism. Not surprisingly, there have been a few internet blog inklings of the unsubstantiated possibility of increasing the probability of such normally common conditions as kidney casts and gall bladder/bile duct involvement. These would necessitate multi-ten thousand people population studies to weed out a single cause from the land fill of known entities, as 50 million Americans contract these conditions during their lifetimes, anyway. Besides, no human studies have been conducted, nor have been deemed worthy of being conducted, on these topics. Considering the vested interests (i.e. no patents, no clinical pipeline) of some of the sources of these rumors, and there being no real beyond arms length data, we chalk this up to purposeful misdirection or typical internet scare tactic mythology.

Although CR/LE mimetics increase LE, they do so less than half as much as true CR. There is a real difference between genuine CR and CR mimetics. In real CR, the intracellular environment and extracellular environment are fuel depleted, while under CR mimetic conditions fuel and energy are ad libitum. The CG pathway must shut down during real CR, but does it have to shut down if only the CR/LE half of the system is strongly and directly affected? We have already seen (5/20/11 Science) that TOR can be compartmentalized in the cell and behave differentially. All known CR mimetics operate on the CR/LE side. Maybe down regulating CG with one of our silver medalists along with a CR mimetic might force TOR to operate in all compartments like it must do in actual CR. Then, we might have a more realistic CR mimicry, and a result more closely approximating ‘the real McCoy’.

Our first primitive attempt to map out the CG/CM and CR/LE system is just a beginning, and we hope that it is a correct beginning, because the medical implications are just altogether stupefying. If this really is that good beginning, then it could function as a template for future pharmaceutical blockbusters, concept pathway expansion and a variety of, yet unsuspected or wholly unknown fruitful applications. From our perspective, the system is coherent and consistent, and seems to explain a lot, in terms if our present knowledge, especially in the way that so many pieces seems to fit together, and so well. Only the future will tell if our idea holds together as a global unifying hypothesis for the aging diseases and life extension phenomena.

Burn extra fat?

Are you one of those individuals, who are in search of some effective weight loss product? Have you tried all kinds of weight loss program and still didn’t manage to get the desired result? Don’t worry. Here’s great news for you. A new product called Herbalife Total Control is launched. It is an effective weight loss solution and can bring in great results for all. This product is very simple and simply reduces the fat in no time.

It works wonder because it is made in such a way that it performs directly with body’s cellular composition to check the cravings for food, enhances metabolic activities. You can use Herbalife Total Control without sacrificing the food you love most. By taking this herbal supplement you can maintain the perfect weight. Moreover, you will also experience an increase in your energy levels.

This weight loss supplement contains the unique mix of components, which helps in weight loss. The ingredients like green tea and yerba mate increases metabolic activities. The other ingredients like damiana, quercetin and DL-phenylalanine support the natural fat burning process. The ginger extract in Herbalife Total Control regulates the working of digestive system. LilyHealth.com

Above all, the ingredients in the this product mend the immune system, check blood pressure and also flushes out the harmful toxins from your body. As a result, you will always feel refreshed and renewed. Herbalife Total Control is absolutely a great way to get back your health back on track. So, visit its official website and order a pack as soon as possible

Foods To Eat For Energy

We all experience low energy from time to time. We live in a culture that is consumed with work and activities. Technology has made us constantly accessible. Sometimes we cannot get away even for a moment and take time for ourselves. The result of these commitments can lead to increased stress levels and rob us of our precious energy. It’s no fun not being able to get up in the morning feeling completely exhausted. We do not want to start our day this way and we can learn strategies to avoid this. Fortunately there are ways to combat low energy by eating the right foods. Food is the primary source for energy for our human body. Certain foods provide more vitamins and minerals. It is important to choose your food wisely so that you can obtain the energy that you need. Particularly important is your morning and afternoon choices as this would be the most important times of day to have optimal energy levels. Your brain needs key nutrients to function productively and requires twice as much energy as the other cells within our body. If the brain does not receive these nutrients you will often suffer from mental stress and overall physical exhaustion.

Perfect Breakfast Foods For Energy

Most people will turn to caffeine and sugar in the quest to increase their morning energy levels. The key is to focus on low glycemic foods because these foods will release energy slowly throughout the day. If you’re seeking something sweet to eat in the morning, a better option would be fresh fruit. The carbohydrates found in fruits break down slowly in the body and thus provide an extended source of energy throughout the day. The fruit provides your brain with the glucose it needs to stay alert. A healthy cereal choice or wholesome oatmeal to eat with your fruit would be ideal. Throughout the day it is a good idea to snack on low glycemic fruit choices like apples, berries and pears as this will provide you with a steady stream of glucose for consistent energy.

Good Lunchtime Choices For Energy

Surprisingly, eating a larger lunch than dinner is a much better choice. In our culture we tend to emphasize eating a very large dinner meal but this is not really sensible. At that point in the day you do not need a large fuel source for energy. Therefore your lunch meal ideally should be the biggest meal that you consume. Some great lunch time choices are a salad which has added to it protein such as chicken or fish and a lot of fresh vegetables like carrots and celery. Don’t forget to add a generous helping of healthy oil such as olive oil to make sure you are getting an adequate omega supply. Another good choice might be some whole wheat bread with protein such chicken, fish or eggs along with fresh vegetables.

Water Provides Energy

Most people underestimate the importance of staying properly hydrated throughout the day. Water is very important to our overall health and can definitely increase your energy levels. Water transports oxygen to your cells therefore providing your body with energy. By drinking at least 8 glasses of water per day you can help decrease your cortisol levels and increase your mental alertness and energy. If you just can’t bring yourself to drink that much water you can incorporate some other healthy beverages like green tea and some low sugar fruit and vegetable juices. Since water can provide all of these vital benefits to your body it would be wise to be sure to include an adequate supply in your daily regime.

Guideline for Good Food Choices For Energy

If you are serious about increasing your energy levels and feeling optimally healthy you should incorporate some of the following foods into your diet.

Whole grains: Ideally 6 servings per day including foods such as wheat bread and brown rice.
Salmon: is an ideal source of protein and is high in omega-3 fatty acids and B vitamins which are a great source of energy.
Beans: Beans are very versatile and give a needed boost of energy. They can easily be added in small amounts to soups, pastas and salads.
Fruit: Fresh fruit as well as dried fruit are very good sources of food for energy. Fruit is naturally low in fat and with such a variety you will never get bored with your choices. Conveniently add fruit by having boxes of raisins or apricots handy as well as dried fruit snacks.
Yogurt: Yogurt is a great choice for a high protein low fat food that will increase your energy. Always keep some handy for an easy and quick pick me up. Adding some fruit to it will increase the energy benefits.
Spinach: This green vegetable contains nutrients that boost energy levels. Spinach along with a variety of other green vegetables is a wonderful way to stay healthy and increase energy.
Clearly the food choices that we make on a daily basis can contribute to our overall feeling of well being and help us to maintain good health. Eating for health and energy is something we all should take more seriously and should help guide the food choices that we make.

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What Is Lactose Intolerance?

Lactose is a type of sugar that is found in butter, cheese, milk and other dairy products. Lactose intolerance is a medical condition in which lactase (an enzyme that helps digest lactose) is not produced in sufficient amounts by the small intestine. Although lactose intolerance can occur at any age, it usually affects young adults and middle aged people. It is more common in people with American or Asian ancestry than it is among Europeans.

Lactose intolerance can be caused by a variety of factors including age, family history, intestinal diseases, infections in the small intestine and bowel surgery. Typical symptoms are flatulence, nausea, indigestion, diarrhoea, irritability, difficulty concentrating, abdominal bloating and abdominal cramps. One might also experience weight loss, constipation and vomiting.

Lactose intolerance is diagnosed with lactose-hydrogen breath test, lactose tolerance test, enteroscopy and examining the stool pH.

As far as the treatment is concerned, avoiding the consumption of dairy products is a best way to prevent the disorder. However, not having dairy products in the diet can lead to deficiency of riboflavin, protein, vitamin D and calcium. Therefore, if you are not consuming milk or other dietary products, then make sure that you regularly take calcium supplements and eat foods that contain calcium such as salmon, sardines, shrimp, leafy greens, oysters and broccoli. Other treatment option for people with lactase deficiency is to add lactase enzymes into their daily dietary routine. Sufferers can consume fermented dairy products, hard cheeses, lactose-free milk, soy milk, goat’s milk and lactose-free buttermilk.

It also makes a good idea for people with lactase deficiency to take a dietary supplement that helps reduce the symptoms of lactose intolerance. There are many lactose intolerance supplements that provides all the essential enzymes that are required to digest lactose.

The use of probiotics may also provide positive health benefits for those that suffer from lactose intolerance.

Probiotics are a type of living bacteria that confer a health benefit on their consumers when taken in the appropriate amounts. They live in the human gastrointestinal tract and act as a balancing agent for harmful gut-bacteria such as Candida albicans and E. coli. A low population of probiotics in your intestine may give rise to a number of bacteria-related health problems such as stomach bloating, indigestion, candidiasis, lactose intolerance, headaches, irritability, anxiety and even colon cancer. The most common forms of intestinal probiotics include Bifidobacteria bifidum and L. acidophilus.

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Let’s Talk About Creatine

Creatine is obtained through your diet via meat, and is also produced in the liver. About half of your daily needs coming from each. For example, if you need 2 grams of creatine and you consume 1 gram from your diet then the other 1 gram will be produced in your body. Creatine is a component of the ‘CP’ part of the ATP-CP (adenosine triphosphate – creatine phosphate) which is part of the metabolic processes that occur during short bouts of exercise such as sprinting and weightlifting.

Stored ATP is an important energy source and is always used during exercise}. ATP has three phosphate molecules. During exercise, muscle contraction results in a phosphate being lost. It now become adenosine diphosphate (ADP) which is instantly recycled back to ATP by the molecule CP. And thus ATP stores are replenished. ATP resynthesised in this way using CP will only last for 10 – 12 seconds. Any longer and ATP will be produced via glucose and fatty acids.

What does creatine do?

If you have high-energy phosphate stores within your body, then you will have the ability to produce much more force. This high-energy-rich compound fuels your muscles during high intense workouts. It allows you to sustain activity longer. But the real treat in creatine is its ability to assist in recovery between sets and workouts. Better recovery will produce better quality of work during exercise. It also produces more quantity in workloads since more can be done without overloading your body beyond its ability to recover fully. This will obviously result in bigger strength and better performance gains. There is a massive amount of well-controlled research showing that creatine supplementation is effective and will result in improvements. If you are training with weights, doing repeated sprints or throws for example, then creatine will help increase your strength, muscle mass and performance. However, it is unlikely to help you if you’re seeking improvement for endurance events.

Should you supplement with creatine?

It is worth mentioning that taking creatine will vary its results depending on the quality and individual. The majority of people however, do better with creatine then without it. There is still some that worry about creatine being safe. It is frequently promoted by the media, using individual case studies, as unsafe. As someone once said, ‘You can prove anything with one case.’ There is no well designed study that shows creatine to be unsafe amongst healthy populations.

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High Calorie Foods

It may seem hard to believe that some people are actually looking to PUT ON weight, but there are. Whether for health reasons, extreme physical conditioning, a temporary condition, a permanent condition or for muscle development, there are times when you or someone you know may need to put on some weight. High calorie foods are a great way to put on this needed weight.

While needing to eat high calorie foods may seem like a “piece of cake” (slight pun intended), it just not that easy. High calories should not mean empty calories. You can’t simply eat donuts and candy bars all day and expect to meet your nutritional needs. Nor can you load up on sugary sodas. Sure these things have calories, but they will not fuel your body with necessary nutrients. You will achieve sugar highs, and sugar crashes, headaches and other physical ailments. If you are eating a diet high in fatty foods such as French fries, you will certainly pack on the pounds, but you will also be at risk for heart disease, increased cholesterol levels, diabetes and other health problems.

The important thing to realize when you are looking for high calorie foods is that DENSE foods are going to be higher in caloric count. For instance, while lettuce, cucumbers and tomatoes are all healthy, they also contain a lot of water. They are not very dense. So simply choosing healthy foods will not meet your high calorie food needs.

When you are searching for high calorie food, you also want to be sure to balance those calories with nutrition. Here are a few top high calorie foods to choose from:

Peanut Butter – you add some extra calories with peanut butter throughout the day. Spread some peanut butter on your whole grain toast in the morning. Or dip your apples in peanut butter for a mid day snack. Other snacks include putting peanut butter between some whole grain crackers or the old standby of peanut butter and celery.

Butter – Choose butter over margarines or butter substitutes, especially those made of saturated fats. Sauté your vegetables in butter (and add some cheese over the top for extra calories along with nutrition). Cook your eggs in butter. And of course, don’t skimp when putting butter on your toast or whole grain rolls.

Breakfast Cereal – No, we’re not talking the sugary sweet breakfast cereal you coveted as a kid! Remember, we are staying away from those sugar highs and lows. Do try some high calorie granola cereals that are packed with nuts and fruit. Add some whole milk, and you have a very nutritious, delicious and high calorie breakfast. You can also add some granola breakfast cereal to yogurt for a great snack or before bedtime treat.

Guacamole – Avocados by themselves are good high calories foods, but add a little sour cream and salsa, and you have a versatile condiment that you can use throughout the day! Add some guacamole to your eggs in the morning, use it as a spread on your sandwiches or wraps for lunch and add to the side of a large taco salad or cheese enchiladas for dinner.

Pure Fruit Juice – Fruit juice is loaded with nutritional content. It also happens to be a high calorie food (or drink rather). You can enjoy fruit juice in the morning, all day and even add it to a smoothie for a mid day or late night snack.

Nuts – Nuts are packed full of protein, nutrients and healthy fats. You can add nuts all throughout your day to add calories to your diet. Keep a baggie of nuts in your purse or car to munch on as you are running errands. Sprinkle almonds on your yogurt. Add nuts to a smoothie.

Dairy Products – Choose from a wide variety of healthy dairy products including milk, eggs, yogurt (especially Greek yogurt) and cheeses. Add cheese to your breakfast, lunch and dinner…and snacks, to increase calories throughout the day. Adding cheese to your vegetables is a great way to add calories to your fruits and vegetables. Snack on them together or melt cheese over vegetables. Try adding cream cheese as a spread to your whole grain sandwiches or wraps. Yogurt is a great base for a smoothie, which can be used for breakfast or a snack.

Whole Grain Carbs – Again, we’re looking to avoid the high sugars. Highly processed carbs in the way of white bread, white rice and potato chips are turned to sugar quickly in the body. Look for whole grain carbs such as 100% whole wheat bread, quinoa and whole grain rice. Try dipping whole grain crackers in hummus for a great mid day snack.

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How Prebiotics Help IBS Sufferers

Here are some facts you might already know about IBS; About 22% of the US population has it and most of those are women between 20 and 35 years old. Medical doctors don’t really have a clue of what it is or how to treat it. You likely have it because of a very poor diet or because of being very high stressed emotionally or a combination of both.

There’s good news

Despite all these facts and how terrible it is to deal with, health experts agree that it is a very treatable digestive condition that will respond very well to a properly modified diet, exercise, and some stress relieving relaxation.

Now some facts you may not know about IBS

Irritable bowel syndrome is primarily a large intestinal disease, or disease of the colon. Although almost no digestion happens in the colon, what does happen down there is extremely vital and directly related to IBS symptoms. Healthy amounts of dietary fibers are needed for a properly functioning colon which is where the digestive system ends and where everything gets sorted out – “out” being the operative word! It’s when all this waste doesn’t get sorted out efficiently that we have many of our IBS disorders come to life.

How prebiotics help

Prebiotics is not just a fancy word fiber. Dietary fibers are a big and important part of prebiotic nutrients but they don’t simply start and end with fibers. Enzymes play an important part as well because they break down the food in the preliminary part of the digestion so the body gets as many nutrients as the food has to offer. Also, food that is not properly broken down will cause digestive problems in the small intestines.

Phenolic compounds are also an important prebiotic nutrient that not only feed the beneficial bacteria in our gut, but inhibit the growth of dangerous bacteria at the same time. Phenols also contain antioxidants that fight a dangerous process that happens in our body called oxidization. Similar to the oxidization that rusts and corrodes metals, inside us it accelerates the aging process and can bring on pre-mature aging conditions such as skin wrinkling and early blindness.

Prebiotic fiber

Since IBS disorders are mostly connected with the large intestine, or colon, it’s here that prebiotic fibers do their most important job. Passing through the intestines without ever getting digested, these fibers end up in the colon where the begin to ferment. This fermentation brings on short-chained fatty acids which make it impossible for dangerous bacteria called pathogens to form cells on the colon wall, which can lead to cancerous polyps if left to grow.

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